While the term “metabolic syndrome” often circulates the health and fitness space, many are puzzled by what it is.

Even fewer know its symptoms, how doctors diagnose it, what causes it, and how you can treat or prevent it. 

In this comprehensive guide, you’ll learn evidence-based answers to all the above and more. 

Metabolic syndrome is a cluster of conditions that increase the risk of health issues such as heart disease, stroke, and diabetes.

Although adopting appropriate lifestyle behaviors can effectively manage or prevent metabolic syndrome, it remains prevalent, affecting approximately 24% of men and 22% of women in the U.S.

Metabolic Syndrome Criteria

To meet the criteria for metabolic syndrome, you have to have at least three of these conditions:


Metabolic syndrome manifests through a variety of symptoms.

Some of the symptoms of metabolic syndrome are easier to spot than others:

  • Waist Size: One of the clearer signs is an enlarged waistline. It’s the kind of symptom you or your doctor can easily see.
  • Subtle Indicators: Some aspects of metabolic syndrome come with no noticeable symptoms. For instance, you might have high blood pressure, elevated triglycerides, or a drop in HDL cholesterol without any distinct signs.
  • High Blood Sugar: If your blood sugar levels rise, you could experience blurred vision, frequent thirst, an increased need to urinate, or fatigue. 

Routine health check-ups are essential. While you can feel or see some symptoms of metabolic syndrome, you might only detect others through regular medical screenings and blood tests.

If your healthcare provider suspects you have metabolic syndrome, they will perform the following tests:

  • Waist circumference: A measurement of 40 inches for men or 35 inches for women is considered a risk factor.
  • Blood Pressure: A consistent reading of 130/85 mmHg or higher may signal high blood pressure, indicating you may be at risk.
  • Blood Sugar: A fasting blood sugar level between 70 and 99 mg/dL is healthy. Levels of 100-to-125 mg/dL suggest high blood sugar or prediabetes, while 126 mg/dL or higher could mean diabetes. 
  • Cholesterol: Healthy HDL levels start at 60 mg/dL and above. Levels below 50 mg/dL for women and 40 mg/dL for men could signify low HDL cholesterol, a factor of metabolic syndrome.
  • Triglycerides: For adults, triglyceride levels should ideally be under 150 mg/dL. Levels persistently above this threshold are indicative of high blood triglycerides.

While this guide pertains mainly to adults, children can also get a diagnosis of metabolic syndrome. For them, specific benchmarks and measurements will be determined by their healthcare provider.

Find the Best Diet for You in Just 60 Seconds

How many calories should you eat? What about “macros?” What foods should you eat? Take our 60-second quiz to get science-based answers to these questions and more.

Take the Quiz

While lifestyle habits affecting your risk of developing metabolic syndrome are under your control, other factors like age and family history are unavoidable.

Modifiable Risk Factors

  • Physical inactivity: Lack of regular exercise can lead to weight gain and poor cardiometabolic health.
  • Poor dietary choices and overeating: Consuming high-calorie, nutrient-poor foods contributes to weight gain and metabolic issues.
  • Inadequate quality sleep: Consistently poor sleep can disrupt metabolic processes and hormone levels.
  • Smoking and alcohol: Both can harm your heart and liver, increasing metabolic syndrome risks.
  • Shift work: Irregular work hours can disrupt the body’s internal clock, leading to metabolic irregularities.

Unmodifiable Risk Factors

Lifestyle Strategies

Changing your lifestyle using the strategies below can help you control or prevent metabolic syndrome.

Medicinal Strategies

If lifestyle modifications aren’t sufficient, your doctor may prescribe medications to help treat metabolic syndrome. Typically, you combine these medications with healthy lifestyle habits.

+ Scientific References