30 Best Flea Medicine for Dogs Without Vet Prescription in 2022


Fleas are one of the most common causes of itchy skin in dogs. Though these pesky insects are small and pack a serious bite, the good news is that you can protect your pup using a high quality flea medicine. What’s even better is that there are prescription-free options to protect your furry friend all year long. 

Keep reading to learn about the 30 best flea medicines for dogs without a vet prescription. All of these products are safe, effective, and will keep these tiny pests at bay. 


Pupper Omega-3 is loaded with high quality omega-3 fatty acids. While fish oil is most commonly used to support joint, heart, and brain health, it also nourishes a healthy skin and coat. This supplement works by keeping your dog’s skin moisturized while keeping his coat soft and shiny. 

Giving your dog Pupper Omega-3 soft chews each day is a proactive way to prevent flea bites. Because this supplement reduces inflammation and keeps the skin healthy, it makes your dog’s skin less attractive to fleas. 


Flea treatment has never been so tasty. Penguin CBD Dog Treats work to give your dog a nourishing boost to protect him against fleas and other pests. CBD oil is a natural pesticide. The best part is that these sweet potato flavored treats also help to ease your dog’s stress and anxiety while also relieving joint pain and sleep problems. 


3. K9 Advantix II Flea, Tick and Mosquito Prevention for Dogs 

K9 Advantix II Flea, Tick and Mosquito Prevention for Dogs is a veterinarian-recommended treatment that works to repel fleas, ticks, and mosquitoes on contact. No biting required! It begins working within 12 hours of application and provides up to four weeks of protection. 

K9 Advantix II Flea, Tick and Mosquito Prevention for Dogs is safe to use on pups 7 weeks and older. 



4. Vet’s Best Flea & Tick Home Treatment Easy Spray 

Vet’s Best Flea & Tick Home Treatment Easy Spray is crafted using a blend of certified natural eugenol from clove plants along with peppermint oil. These essential oils work to kill fleas and ticks. The gentle mist is easy to apply and provides great coverage. 

Vet’s Best Flea & Tick Home Treatment Easy Spray is safe to use on dogs 12 weeks and older. 


5. Frontline Gold Flea & Tick Treatment 

Protect your dog all month long with Frontline Gold Flea & Tick Treatment. This topical treatment is formulated to kill fleas and ticks while preventing re-infestations. It’s easy to use and begins killing pests within 30 minutes of application. 

Frontline Gold Flea & Tick Treatment is safe for use on dogs 8 weeks and older.